Rekombinanter MTDH Antikörper (AA 475-525)
Kurzübersicht für Rekombinanter MTDH Antikörper (AA 475-525) (ABIN7795651)
Target
Alle MTDH Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 475-525
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Verwendungszweck
- Rabbit anti-LYRIC/AEG1 Recombinant Monoclonal Antibody [BLR258L]
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Aufreinigung
- Purified
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Immunogen
- Between 475 and 525
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Isotyp
- IgG
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Applikationshinweise
- Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,150 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,150 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 250 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- MTDH (Metadherin (MTDH))
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Andere Bezeichnung
- LYRIC/AEG1
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Hintergrund
- Astrocyte elevated gene-1 protein (AEG1) is also known as metadherin. AEG1 AEG1 promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. It also promotes lung metastasis and has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. AEG1 induces chemoresistance.
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Gen-ID
- 92140
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UniProt
- Q86UE4
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
Target
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